Page 30 - THE 14th GRADUATE INTEGRITY : GI14

This reaction forms hypochlorous and hydrochloric acid along with free oxygen radicals.

Hypochlorous and hydrochloric acid cause most of the toxic effects attributed to chlorine gas. These acids
are produced by the reaction of chlorine (Cl2) with water. [11]
Prior knowledge from literature review, chlorine exposure results in a direct chemical toxicity to
the airways that is potentiated by the ensuing inflammatory response. Oxidative damage to airways may

result during either stage of illness. Acute airways obstruction followed by airways remodeling and/or
airways hyperresponsiveness may be seen following chlorine exposures both in animal models and in
humans. The results of human chlorine inhalation may range from acute overwhelming intoxication with

acute lung injury and/or death to intermittent or repeated accidental or unintentional occupational
exposure. In humans, recommended treatment for RADS/acute irritant-induced asthma once established is
similar to that for asthma generally (i.e., bronchodilators and systemic corticosteroids for management of
acute exacerbations and inhaled corticosteroids with bronchodilators if necessary for chronic maintenance

therapy). However, patients treated with these agents can continue to exhibit abnormal lung function. [13,14]

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ǰǰ To identified cardiopulmonary effect due to incompetency architectural design in a tropical climate

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ǰǰ After literature review, the most suitable question is how chlorinated vapor could effect human

lungs in long term. That would be interesting if research could answer the question of chlorine effect
separated by age group and timing of exposure.
Due to case-controlled study design, data gathering are collected from chest x-ray. Group of
experiment are divided into control group and experimental group. Control group is group of people who

do not work in aforementioned worksite while experimental group is exposure group who expose with
chlorine and air craft pollution without safety architectural design. Our case-controlled study had 103
patients which include 52 patients in control group and 51 patients in experimental group. Criteria of

exposure group in poor architectural design are no temperature control but almost of temperature in
working hour is over than 30 degree Celsius, no evaporation control which has no partition or any wall to
prevent chlorine vapor and exposure of worker during chlorine filling on the top of water tank while they
are still exposure to pollution from aircraft. However, almost of experimental group started working on

experimental environment before 30 years-old until the date of examination with chest x-ray. [21]
Example of incompetency architectural design in our study which promote chlorine vaporization
in tropical climate. There are few opening system of chlorine tank to worker beside them in Figure[1]

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